Thinking loudly about networked beings. Commonist. Projektionsfläche. License: CC-BY
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Russell's Teapot

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Unfortunately, NASA regulations state that Bertrand Russell-related payloads can only be launched within launch vehicles which do not launch themselves.
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tante
5 days ago
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Engineers "fixing" philosophical problems
Oldenburg/Germany
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2 public comments
Covarr
5 days ago
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I'm crowdfunding a project to launch two slices of bread into orbit around the earth on opposite sides, so the whole world can be a sandwich.
Moses Lake, WA
vanbcguy
4 days ago
I'd kick in $5 for that...
benzado
3 days ago
The Earth became a sandwich over ten years ago, thanks to the hard work of volunteers! http://scourist.com/2006/06/09/0009-earth-sandwich/
CaffieneKitty
2 days ago
The most complete idiot sandwich ever. :-)
alt_text_bot
5 days ago
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Unfortunately, NASA regulations state that Bertrand Russell-related payloads can only be launched within launch vehicles which do not launch themselves.

Verdacht auf Abgasbetrug: Schwere Vorwürfe gegen Daimler

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Die betroffenen Motoren sind in vielen Mercedes-Klassen eingebaut | Bildquelle: dpa

Daimler hat in der Abgasaffäre bei Diesel-Autos möglicherweise noch massiver manipuliert als bisher bekannt. Das geht nach Recherchen von WDR, NDR und "SZ" aus einem Durchsuchungsbeschluss hervor. Mehr als eine Million Fahrzeuge könnten betroffen sein. Von Lena Kampf. [mehr]

Meldung bei www.tagesschau.de lesen

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tante
14 days ago
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Die deutsche Autoindustrie ist in etwa so vertrauenswürdig wie Donald Trump.
Oldenburg/Germany
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Boris Palmer zu Umgang mit Flüchtlingen: Verpflichtende DNA-Tests

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Tübingens grüner Oberbürgermeister fordert erneut strengere Regeln für Geflüchtete. Diesmal geht es um Speichelproben in bestimmten Fällen. mehr...
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tante
15 days ago
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Die Grünen kriegen ihren tübinger Rassisten nicht in den Griff.
Oldenburg/Germany
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The Philosophy Force Five vs the Scientismists

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Some people are going to say this was an unfair portrayal of Sam Harris, but considering I didn't have him say anything openly sexist, I'd say it was pretty generous.
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tante
37 days ago
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The Philosophy Force Five vs the Scientismists
Oldenburg/Germany
popular
35 days ago
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Studie zu Elektroautos: Tonnenweise Treibhausgase

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Die schwedische Energieagentur hat sich die Klimabilanz bei der Batterieherstellung von E-Autos angeschaut. Ergebnis: Sieht nicht gut aus. mehr...
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tante
37 days ago
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Elektroautos sind ja schön und gut, die Batterieherstellung ist allerdings weiterhin ziemlich dreckig.
Oldenburg/Germany
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Increasing Pharma Profits Come from Price Bumps, Not New Drugs

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When Martin Shkreli made news in 2015 for jacking the price of Daraprim, a drug used to prevent certain parasitic infections in HIV patients, from $13.50 per pill to over $750 per pill he was basically cast as a comic book villain. A craven boyman cashing in on the needs of the sick. He became an outlier, a pharma celebrity posed in relief to an industry that otherwise remained faceless.

Shkreli wasn't really an outlier though. He was just a part of the pharma continuum. In the pharmaceutical industry, some 80 percent of the growth in profits in 2015 are attributable to price increases rather than new drugs. This is according to a new op-ed in Stat from Robin Feldman, director of the Institute for Innovation Law at UC Hastings College of the Law and a frequent patent law commentator. Feldman is currently pitching a new book: Drug Wars: How Big Pharma Raises Prices and Keeps Generics Off the Market.

"Between 2010 and 2014, prices for the 30 best-selling drugs in the U.S. rose eight times faster than inflation," Feldman writes. "Americans bear the brunt of these increases. For example, the liver failure drug Syprine, which costs less than $400 a year in some countries, has a list price around $300,000 in the United States."

In the US, the difference between an affordable drug and otherwise is mostly determined by whether or not a generic version of the drug exists. If it does not exist, then the drug manufacturer can basically charge whatever it wants. If it does exist, competition invariably drives the price down. So, the task of the drug maker is delaying for as long as possible the introduction of the generic drug. Drug companies have made an art of this.

There's a logic behind blocking generics, to an extent. Drug developers are given a window of exclusivity in the first place—where only a particular company can make a drug—because developing new drugs costs a lot of money. It seems fair that they should have a chance to recoup some of that. Otherwise, there wouldn't be much incentive to make new drugs.

But it's hardly that simple. If a drug company can somehow extend an drug's window of exclusivity, then it doesn't even have to make something new, right? So that's what happens.

Feldman outlines several different ways a drug company can go about doing this. The most simple is just asking the FDA to not approve generic versions, but there are other methods, such as starting clinical trials for a potential new application of a particular drug. In some cases, generic drug makers and name-brand drug makers reach deals where the generic firm voluntarily agrees to not enter the market in exchange for some payout.

That this stuff is happening isn't news, but it's worth keeping in mind that things were plenty fucked before Shkreli hit the scene and they will remain so so long as the law allows it.



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tante
39 days ago
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Pharma's profits come from increasing prices of existing rugs not the development of new ones.
Oldenburg/Germany
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