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The Philosophy Force Five vs the Scientismists

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Some people are going to say this was an unfair portrayal of Sam Harris, but considering I didn't have him say anything openly sexist, I'd say it was pretty generous.
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tante
6 days ago
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The Philosophy Force Five vs the Scientismists
Oldenburg/Germany
popular
4 days ago
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Studie zu Elektroautos: Tonnenweise Treibhausgase

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Die schwedische Energieagentur hat sich die Klimabilanz bei der Batterieherstellung von E-Autos angeschaut. Ergebnis: Sieht nicht gut aus. mehr...
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tante
6 days ago
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Elektroautos sind ja schön und gut, die Batterieherstellung ist allerdings weiterhin ziemlich dreckig.
Oldenburg/Germany
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Increasing Pharma Profits Come from Price Bumps, Not New Drugs

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When Martin Shkreli made news in 2015 for jacking the price of Daraprim, a drug used to prevent certain parasitic infections in HIV patients, from $13.50 per pill to over $750 per pill he was basically cast as a comic book villain. A craven boyman cashing in on the needs of the sick. He became an outlier, a pharma celebrity posed in relief to an industry that otherwise remained faceless.

Shkreli wasn't really an outlier though. He was just a part of the pharma continuum. In the pharmaceutical industry, some 80 percent of the growth in profits in 2015 are attributable to price increases rather than new drugs. This is according to a new op-ed in Stat from Robin Feldman, director of the Institute for Innovation Law at UC Hastings College of the Law and a frequent patent law commentator. Feldman is currently pitching a new book: Drug Wars: How Big Pharma Raises Prices and Keeps Generics Off the Market.

"Between 2010 and 2014, prices for the 30 best-selling drugs in the U.S. rose eight times faster than inflation," Feldman writes. "Americans bear the brunt of these increases. For example, the liver failure drug Syprine, which costs less than $400 a year in some countries, has a list price around $300,000 in the United States."

In the US, the difference between an affordable drug and otherwise is mostly determined by whether or not a generic version of the drug exists. If it does not exist, then the drug manufacturer can basically charge whatever it wants. If it does exist, competition invariably drives the price down. So, the task of the drug maker is delaying for as long as possible the introduction of the generic drug. Drug companies have made an art of this.

There's a logic behind blocking generics, to an extent. Drug developers are given a window of exclusivity in the first place—where only a particular company can make a drug—because developing new drugs costs a lot of money. It seems fair that they should have a chance to recoup some of that. Otherwise, there wouldn't be much incentive to make new drugs.

But it's hardly that simple. If a drug company can somehow extend an drug's window of exclusivity, then it doesn't even have to make something new, right? So that's what happens.

Feldman outlines several different ways a drug company can go about doing this. The most simple is just asking the FDA to not approve generic versions, but there are other methods, such as starting clinical trials for a potential new application of a particular drug. In some cases, generic drug makers and name-brand drug makers reach deals where the generic firm voluntarily agrees to not enter the market in exchange for some payout.

That this stuff is happening isn't news, but it's worth keeping in mind that things were plenty fucked before Shkreli hit the scene and they will remain so so long as the law allows it.



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tante
8 days ago
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Pharma's profits come from increasing prices of existing rugs not the development of new ones.
Oldenburg/Germany
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Debatte Finanzkasino: FDP und CDU belügen die „Mitte“

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Die Parteien bedienen Millionäre, anstatt Facharbeiter zu entlasten. Sie werben um die „Mitte“, sehen sie aber nur als Stimmvieh für klassische Klientelpolitik. mehr...
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tante
8 days ago
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FDP ist und war immer Partei der Besserverdienenden. Niemand anders sollte drauf reinfallen.
Oldenburg/Germany
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Saturday Morning Breakfast Cereal - Spandrels

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Click here to go see the bonus panel!

Hovertext:
The moment you stop trying to do anything to make the other person like you? That's true love.

New comic!
Today's News:
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tante
9 days ago
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The lies people tell each other
Oldenburg/Germany
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2 public comments
francisga
16 days ago
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"Should we change our pants?"
Lafayette, LA, USA
CallMeWilliam
16 days ago
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and then you come home to strawberry rhubarb cocktails that you actually like.

Cowboy Bebop is returning as a live-action series

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Cowboy Bebop, one of the best known anime of all time, will be adapted into a live-action TV show from Tomorrow Studios, Variety reports. Thor: The Dark World and Thor: Ragnarok screenwriter Chris Yost will pen the series, while Sunrise, the studio behind the original show, is attached to executive produce.

Cowboy Bebop originally aired in 1998 in Japan as a 26-episode series, though its late night run on Cartoon Network’s Adult Swim in 2001 helped buoy it to success in the United States. Set in a dystopian future in 2071, Cowboy Bebop imagines an Earth that has been long abandoned and humans who roam the stars. The show follows Spike Spiegel and a misfit group of bounty hunters as they search for the next big score and grapple with...

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sarcozona
18 days ago
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I won't let this take Ed away from me
tante
18 days ago
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Cowboy Beebop gets the live action treatment.

There is no god. Nothing is sacred. Life is pain.
Oldenburg/Germany
fanguad
18 days ago
Hold out hope. It *could* be good. Just not very likely.
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